Testicular tumours: a retrospective study of 154 cases

ABSTRACT

In a retrospective study of all cases of testicular tumors managed at the National Cancer Institute, Cairo University and Kasr El-Aini University Hospital during 7 years [from 1986 till 1992], the files of the patients had been revised in the Statistic Departments. The results obtained showed that 154 cases of testicular tumors were managed during that period. Ninety six cases presented with a testicular tumor proved to be malignant after inguinal orchiectomy, 32 cases referred from outside with a testicular biopsy or orchiectomy which proved to be malignant and 26 cases referred for biopsy from the medical oncology departments with testicular relapse of leukemia or non-Hodgkin's lymphoma. Eleven cases had a history of undescended tests, 8 cases had a history of congenital inguinal hernia and 12 cases had a history of previous inguinoscrotal operations. The age of patients ranged between 9 months and 73 years with a mean age of 27.34 years. Tumors of the right testis [51.9%] were more common than the left [31.8%]. The commonest pathological type was seminoma [28.6%] and the rarest was choriocarcinoma [1.3%]. The commonest presentation was only a testicular swelling [71.43%]. Elevation of human chorionic gonadotrophin occurred in 77.9% of the cases while elevation of alpha fetoprotein occurred in 51.7% only. Pelviabdominal sonography showed enlarged abdominal lymph nodes in 45.2%, while pelviabdominal CT showed enlarged nodes in 30.8%. Pedal lymphography showed signs of positive abdominal lymph nodes invasion in 44.9%. The commonest management done was orchiectomy and chemotherapy [31.8%]. Retroperitoneal lymph nodes dissection was done in 3 cases. One case was positive for metastases and 2 cases were negative