Tumour necrosis factor in squamous cell carcinoma of urinary bladder

ABSTRACT

This study aimed to demonstrate the role of tumor necrosis factor [TNF] in malignancy. TNF level has been estimated by ELISA techniques method in 30 patients with cancer bladder and 10 normal control subjects. It was found that preoperative TNF levels were significantly higher in comparing to the normal control subjects, and this level dropped postoperatively in 80% of the cases. These findings led to the conclusion that TNF may be used as a tumor marker for regular check up and that the TNF level may be used to assess the radicality of the operative procedure if the postoperative sample was taken after a longer duration in the absence of surgical complications