Prevalence of microalbuminuria in diabetic children as an early indicator of reversible diabetic nephropathy

ABSTRACT

Diabetic nephropathy is proved to be the most common cause of death in type I diabetes and microalbuminuria is the early sign in the reversible stage of diabetic nephropathy. 70 patients with insulin dependent diabetes mellitus with age ranged between 3-12 years were subjected to full clinical examinations and laboratory analysis for microalbuminuria estimation, kidney function tests and fasting and post-prandial blood sugar levels. Of these diabetic children, 26 patients [37%] showed microalbuminuria. There was significant difference between both groups with and without microalbuminuria as regarding duration and severity of diabetes. But there was insignificant difference as regarding age, sex and kidney function tests. There was also a positive correlation between level of microalbuminuria and both duration and severity of diabetes