Stability of sulphacetamide eye drops at higher temperature
JPMA-Journal of Pakistan Medical Association. 1983; 33 (7): 168-172
em Inglês
| IMEMR
| ID: emr-3540
ABSTRACT
Sulphacetamide solutions at higher temperature degrade to its hydrolysed product, sulphanilamide, with a first-order rate constant. The degraded products are identified and characterized by chromatography and spectrophotometry. Attempts are made for the evaluation of kinetics, entropy and enthal changes activation energy and frequency factors during heating of sulphacetamide solutions. The determination of these thermodynamic elements is useful in prediction of the stability of sulphacetamide eye-drop formulation at elevated temperatures
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Soluções Oftálmicas
/
Estabilidade de Medicamentos
/
Temperatura Alta
Idioma:
Inglês
Revista:
J. Pak. Med. Assoc.
Ano de publicação:
1983
Similares
MEDLINE
...
LILACS
LIS