Phenobarbitone pretreatment in bilharzial surgical patients receiving ether anesthesia: effect on some liver enzymes

ABSTRACT

The effect of phenobarbitone pretreatment was studied on bilharzial patients operated on for splenectomy. The pretreatment with phenobarbitone did not adversely affect bilharzial surgical patients receiving ether anaesthesia. The depressing effect of ether anaesthesia on some enzymes could even be overcome, particularly those sharing in carbohydrate metabolism. The enzymes involved in phosphate transfer and lipid catabolism were inhibited