Inhibitation of gluconeogenic enzymes in rat liver after intraperitoneal sublethal doses of dimethoate
Bulletin of High Institute of Public Health [The]. 1995; 25 (3): 699-704
em Inglês
| IMEMR
| ID: emr-36768
ABSTRACT
Male Wistar rats were injected with dimethoate intraperitoneally for 7 successive days. The treated animals suffered from a significant loss in the body weight and liver weight compared to the control group. Two gluconeogenic enzymes phosphoenolpyruvate carboxykinase [PEPCK] and Fructose 1.6-bisphosphatase [FBP ase] were examined in liver. A significant decrease in activity of both enzymes was found in the treated rats. This inhibition was at a significant value of P<0.05 for FBP ase and P<0.001 for PEPCK
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Ratos
/
Deficiência de Frutose-1,6-Difosfatase
/
Fígado
Idioma:
Inglês
Revista:
Bull. High Inst. Public Health
Ano de publicação:
1995
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