Enaminonitrile in heterocyclic synthesis: synthesis of thiazolo [4,5-b] pyridine and thiazolo [4,5-d] pyrimidine derivatives
Egyptian Journal of Chemistry. 1995; 38 (1): 67-76
em Inglês
| IMEMR
| ID: emr-37100
ABSTRACT
Ammoniumn- phenyldithiocarbamate reacted with bromomalononitrile and alpha chloroacetylacetone to afford thiazole derivatives 3a, b. Compound 3a reacted with benzylidenemalononitrile, malononitrile, phenylisothiocyanate, benzoylisothiocyanate, trichloroacetonitrile, formamide, carbon disulphide and triethylorthoformate to afford thiazolo [4,5-b] pyridine derivatives 6,9 and thiazolo [4,5-d] pyrimidine derivatives 13, 16, 18, 19, 20 and 21. Most of the synthesized products show high fungicidal and bactericidal activities
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Piridinas
/
Pirimidinas
/
Tiazóis
Idioma:
Inglês
Revista:
Egypt. J. Chem.
Ano de publicação:
1995
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