Synthesis of some substituted 9-anilinoacridines and 4-anilinoquinolines of possible antitumor activity

ABSTRACT

3-amino-4-methoxybenzoie acid methyl ester and 3-amino- 4-methoxy-6- methane sulphonamidobenzoic acid methyl ester were condensed with 4, 7-dichloroquinoline, 4-chloroquinaldine, 9-chloroacridine and 2-methoxy-6,9-dichloro acridine. The anilide esters obtained were reduced to the corresponding alcohols from which the N-methylcarbamate derivatives were prepared as possible antitumour agents