Synthesis and reactions of 4- [benzyl] -6- [2- [5, 6, 7, 8-tetrahydronaphthyl]] -3 [2H] -one

ABSTRACT

The present investigation deals with the synthesis and some reactions of 4-benzyl-6-[2-[5,6,7,8-tetrahydronaphthyl]]- pyridazin- 3[2H]-one. Such compound was prepared by base catalysed condensation of benzaldehyde with 6-[2-[5,6,7,8]- tetrahydronaphthyl]] -4, 5-dihydropyridazin-3[2H]-one [1]. The reaction proceeded smoothly to give 4-benzyl-6-[2-[5,6,7,8- tetrahydronaphthyl]]-pyridazin -3[2H]-one [3], via prototropic rearrangement of the intermediate [5,6,7,8-tetrahydronaphthyl]]- pyridazin-3[2H]-one [2]