Immunodiagnosis of cryptosporidiosis in Children with chronic diarrhea in El-Menya governorate

ABSTRACT

ELISA, as well as stool analysis were used to evaluate the presence of Cryptosporidiosis in 285 suspected cases among children in El-Minia Governorate. Sera from 259 children with chronic diarrhea, 23 [8.8 percent], 7 [2.7 percent] and 5 [1.9 percent] were positive for specific IgG, IgM and IgG and IgM to Cryptosporidium respectively. Of the 259, 18 [6.9 percent] stool samples were positive for Cryptosporidium oocysts. Of the 26 asymptomatic cases, 2[7.6 percent] were positive for oocysts in their stool samples and 3 [11.5 percent] were positive for specific IgG antibodies but no one had IgM. Detection of specific IgG increased in the two to four years -old age -group. It was concluded that, serological diagnosis of Cryptosporidium infection will be useful in establishing more accurate prevalence rate