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Hypnozoites resistant to primaquine: the first case reported from Kuwait
KMJ-Kuwait Medical Journal. 1995; 27 (3): 237-40
em Inglês | IMEMR | ID: emr-38069
ABSTRACT
Primaquine is the only drug currently in use to eliminate the gametocytes of Plasmodium Vivax [PV] and also, destroys hypnozoites [latent liver stages] of PV and Plasmodium ovale [PO] and thereby effects a radical cure. The usual dose for antirelapse therapy for PO infection is 15 mg base daily for 14 days or once weekly for 8 weeks. Radical cure of PV in some parts of South-East Asia and Oceania requires higher total doses of primaquine [15-22.5 mg base daily for 14 days or once weekly for 8 weeks]. In Kuwait, 30 mg of primaquine is given weekly for 8 weeks as a radical cure according to WHO recommendations. In this paper, we report a case of a patient in whom, hypnozoites were resistant to primaquine at 45 mg weekly, for 8 weeks
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Primaquina / Resistência a Medicamentos / Malária Idioma: Inglês Revista: Kuwait Med. J. Ano de publicação: 1995

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Primaquina / Resistência a Medicamentos / Malária Idioma: Inglês Revista: Kuwait Med. J. Ano de publicação: 1995