phytochemical screening of some solanaceous plants phytosterol and fatty acid constituents of solanum elaeagnifolium and solanum nigrum in addition to pharmacological and antimicrobial investigation.

ABSTRACT

The phytochemical screening of 19 Solanaceous plant samples were performed. Alkaloids were detected in 13 samples, flavonoids in 6 samples, phytosterols, terpenoids were detected in 11 and 7 samples while, tannins only in 2 samples. The phytosterol and fatty acid constituents in the lipids contents of Solanum elaeagnifolium and Solanum nigrum were determined by GLC. Sqalene, stigmasterol and beta-sitosterol are the main constituents in the plant samples besides campasterol in the seeds and stems of S. elaeagnifolium. Palmitic and palmitoleic acids are the main constituents in both plant species beside stearic and linoleic acids in the seeds of S. nigrum. All the examined extracts of both S. elaeagnifolium and S. nigrum induced a minimal stimulatory effect when tested on isolated rabbit jejunum and moderate relaxant effect of both rate and amplitude on isolated heart. The antimicrobial activity of the examined extracts of the both plants shows activity against B. subtilis and higher activity against E. coli and S. aureus