Detection of Crimean-congo hemorrhagic fever virus antibodies in man and in animals

Crimean-Congo hemorrhagic fever [CCHF] virus antibody survey was carried out in saudi Arabia on sera from man and several animal species using the reversed passive hemagglutination inhibittion [RPHI] test. Antibodies were found in 3/354 humans, 88/2162 sheep, 14/432 goats and 1/182 cattle. Camels and horses sera gave negative result. For the sake of comparison RPHI-positive sera and some selected negative sera were tested by indirect immunofluorescence [IF] and immunodiffusion [ID]. The results revealed that RPHI test is more sensitive than either of the two tests