Immunohistopathological status of the skin in cases infested with three species of mites

ABSTRACT

This study was performed on 80 patients with clinical manifestations of scabies. Sarcoptes scabiei adult or larva was isolated from 39 patients [48.8%]. Dermanyssus gallinae [red poultry mite] and Dermatophagoides sp. were isolated from 6 and 5 patients, respectively. Punch biopsies were taken from the patients, stained with hematoxylin and eosin and direct immunofluorescence stain to study the immunopathological status of the skin infested with 3 species of mites. The results declared that the pathological changes and the immunoglobulin deposition in the skin were nearly similar, regardless of the type of the causative mite, except of the presence of burrows in Sarcoptes scabiei