New Egyptian Journal of Medicine [The]. 1996; 14 (5): 232-38
em Inglês
| IMEMR
| ID: emr-42711
ABSTRACT
The present work was designed to evaluate the effects of some antioxidants; vitamin E, vitamin C, deferoxamine and the ACE inhibitors [captopril and enalapril] on renal functions and peroxidative changes in glycerol-induced ARF in the rat. Drugs were given before and after induction of ARF by im injection of hypertonic glycerol solution. Serum and urinary urea, creatinine concentrations, urinary/serum urea and creatinine ratios, creatinine clearance, serum malondialdehyde as well as renal reduced glutathione concentrations were estimated. All the above mentioned drugs showed a significant renoprotective effect by improving the marked deterioration of the estimated kidney function tests in the uremic rats
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Peroxidases
/
Inibidores da Enzima Conversora de Angiotensina
/
Injúria Renal Aguda
/
Glicerol
/
Rim
/
Testes de Função Renal
/
Antioxidantes
Limite:
Animais
Idioma:
Inglês
Revista:
New Egypt. J. Med.
Ano de publicação:
1996
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