study of some atherogenic risk factors in children

ABSTRACT

Atherosclerosis is a multifactorial reversible disease in childhood age. So, the early identification of young high risk population offers an opportunity for the early initiation of preventive measures [Kwiterovich, 1989]. This study included 100 children [54 males and 46 females], their ages ranged from 6 to 9 years, they were classified into; a target group [50] with positive family history of premature CAD and a control group [50] without this history. They were subjected to history taking, clinical examination and lab investigations. The results revealed that DM and hypertension were atherogenic risk factors. The target group showed a significant difference regarding TC, LDL-C and LDL-C/HDL-C ratio compared to the control group, again these were potent atherogenic risk factors. Regarding TG and HDL-C, there was no significant statistical difference. The study recommended screening program for children over 2 years, especially those with positive family history of premature CHD to start early preventive measures: