Study on virulence factors of pasteurella multocida isolated from different sources
New Egyptian Journal of Medicine [The]. 1996; 14 (Supp. 6): 60-64
em Inglês
| IMEMR
| ID: emr-42742
ABSTRACT
In this study 15 Pasteurella multocida isolates [collected from different sources] were investigated for virulence factors, namely, capsular and outer membrane protein [OMP] components, binding properties to fibrinogen and fibronectin and the bacterial surface hydrophobicity. All serotype A [7 isolates] demonstrated hyaluronic acid capsule when tested by the hyaluronidase depolymerization test. The electrophoretic analysis of the OMP preparations revealed 37 kDa protein-b and s in all serotype A and E isolates, which was analogous to the major P. multocida H protein or porin H [channel-forming protein]. OMP preparations from serotype B isolates revealed 32 kDa protein b and s, similar to the characteristic protein b and s found in all P. multocida serotype B isolated from hemorrhagic septicemia-positive cases. Other protein b and s, 21, 24, 30, 31, 34, 36, 53 and 64 kDa were demonstrated in different serotypes, which could be related to the bacterial adhesion characteristics
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Proteínas da Membrana Bacteriana Externa
/
Virulência
/
Fibrinogênio
/
Fibronectinas
/
Pasteurella multocida
Idioma:
Inglês
Revista:
New Egypt. J. Med.
Ano de publicação:
1996
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