Pituitary-gonadal abnormalities in Egyptian children and adolescents with chronic renal insufficiency
New Egyptian Journal of Medicine [The]. 1996; 15 (1): 4-10
em Inglês
| IMEMR
| ID: emr-42744
ABSTRACT
Delayed sexual maturation is one of the problems facing survivors with chronic renal insufficiency [CRI]. Follicle stimulating hormone [FSH], luteinizing hormone [LH], prolactin [PRL], testosterone [TEST] and estradiol [ESTR] were estimated in 34 patients with CRI as compared to 20 healthy subjects. Some patients were given drug therapy [bromocriptin or clomiphene citrate or both of them] and their hormone profiles were reevaluated after the end of the therapy. This was a trial to outline the effects of CRI on the pituitary-gonadal axis and to investigate some modalities of drug therapy in addition to hemodialysis [HD]. The study revealed low FSH level in 23.4% of patients, low LH in 26.47% of patients and hyperprolactinemia in 50% of them. ESTR was found low in 60% of female patients while TEST was low in 89.4% of male patients. The study found that the worst the rental function the lower the FSH level [p <0.05] and the higher the PRL level [p <0.05]. No significant differences were found on comparing patients under regular HD to those on conservative treatment
Buscar no Google
Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Hipófise
/
Bromocriptina
/
Criança
/
Adolescente
/
Clomifeno
/
Gônadas
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
New Egypt. J. Med.
Ano de publicação:
1996
Similares
MEDLINE
...
LILACS
LIS