New pyridazinedione derivatives: synthesis and antimicrobial activity
Alexandria Journal of Pharmaceutical Sciences. 1997; 11 (1): 9-12
em Inglês
| IMEMR
| ID: emr-43824
ABSTRACT
Various substituted and unsubstituted pyridazine-3, 6-diones were prepared in a good yield via the reaction of p-nitrobenzoic acid hydrazide with diacyltartaric acid anhydride, maleic or phthalic acid anhydride [I-IV]. Then, each pyridazinone derivative was condensed with urea, thiourea or hydrazine to afford the corresponding pyridazinotriazine or triazolopyridazine derivatives [V-XVI], respectively. The spectral properties of the products were studied and the antimicrobial activity was evaluated
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Piridazinas
/
Anti-Infecciosos
Idioma:
Inglês
Revista:
Alex. J. Pharm. Sci.
Ano de publicação:
1997
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