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New pyridazinedione derivatives: synthesis and antimicrobial activity
Alexandria Journal of Pharmaceutical Sciences. 1997; 11 (1): 9-12
em Inglês | IMEMR | ID: emr-43824
ABSTRACT
Various substituted and unsubstituted pyridazine-3, 6-diones were prepared in a good yield via the reaction of p-nitrobenzoic acid hydrazide with diacyltartaric acid anhydride, maleic or phthalic acid anhydride [I-IV]. Then, each pyridazinone derivative was condensed with urea, thiourea or hydrazine to afford the corresponding pyridazinotriazine or triazolopyridazine derivatives [V-XVI], respectively. The spectral properties of the products were studied and the antimicrobial activity was evaluated
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Piridazinas / Anti-Infecciosos Idioma: Inglês Revista: Alex. J. Pharm. Sci. Ano de publicação: 1997

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Piridazinas / Anti-Infecciosos Idioma: Inglês Revista: Alex. J. Pharm. Sci. Ano de publicação: 1997