Synthesis of some new coumarin derivatives incorporated to heterocyclie aromatic rings
Egyptian Journal of Pharmaceutical Sciences. 1997; 38 (1-3): 1-11
em Inglês
| IMEMR
| ID: emr-44522
ABSTRACT
3-bromo-4-methyl-7-coumarinyloxy acetic acid hydrazide was condensed with some aromatic aldehydes to give Schiff's bases 5 a-e which cyclized to thiazolidine derivatives 6a-e. Also, 7-O-[N-[succinimido] acetamido]-and 7-O-[[2-oxy-3-indolinylidene] acetic acid hydrazido]-3-bromo-4-methyl coumarins [3] and [4] were prepared. 7-O-[N-[sulfa drug] carbonyl methoxy]-3-bromo-4-methylcoumarin derivatives 10a-f were prepared via the formation of the acid chloride 9. Some of the new coumarin derivatives showed satisfactory results as molluscicidal activity against Biomphalaria alexandrina snails
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Cumarínicos
/
Compostos Heterocíclicos
Idioma:
Inglês
Revista:
Egypt. J. Pharm. Sci.
Ano de publicação:
1997
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