Synthesis of some new indole derivatives of possible antimicrobial activity

ABSTRACT

A series of indolyl arylidene hydrazones 2 [c,d], indolylamidothiazolidin-4-ones 3 [a-d], pyrazoline [4], pyrazolidin- dione [5], pyrazolone [6], 3-[3-cyano-4-aryl-2-imino [1H]-pyridin-6-yl]-indoles 8 [a-g] and 3-[3-cyano-4-aryl-2-thioxo [1H]-pyridin-6-yl]-indoles 9 [a-e] were synthesized. Some of the new compounds showed considerable antimicrobial activity against Gram +ve bacteria, yeast and fungi