Effect of insulin on the buccal absorption of sulfathiazole sodium
Journal of Drug Research of Egypt. 1984; 15 (1-2): 211-215
em Inglês
| IMEMR
| ID: emr-4535
ABSTRACT
The effect of insulin on absorption of sulfathiazole from the buccal cavity was studied in volunteers of both sex. Insulin was shown to increase the amount absorbed, and to change significantly the rate constant of absorption [Ka] and the half life of the fraction remaining of sulfathiazole in the buccal cavity [t ']. The obtained results are in agreement with previously done works on laboratory animals. The results illustrate the usefulness of the buccal absorption model for studies on drug interaction during absorption
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Sulfatiazóis
/
Interações Medicamentosas
Idioma:
Inglês
Revista:
J. Drug Res. Egypt
Ano de publicação:
1984
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