Efficacy of transrectal microwave hyperthermia [TRMH] in treatment of abacterial prostatitis

ABSTRACT

Thirty patients with chronic abacterial prostatitis were randomly divided into two groups [15 cases each]. Group I was given medical treatment in the form of oral minocycline [100 mg] twice daily for three weeks, whereas group II was given the same medical treatment course combined with eight sessions [1-hour each thrice weekly] of TRMH [43 C] to the prostate. The efficacy of the treatment was evaluated by the effect on symptoms, clinical signs, white blood cells [WBCs] in expressed prostatic fluid [EPF], pre- and post-prostatic massage urinalysis and urodynamic measurements [flowmetry]. The results showed marked improvement of the symptoms and signs among group II patients [excellent results in six, good in three, fair in two and poor in four] and less improvement among group I patients [excellent in three, good in three and poor in nine] as assessed clinically. When a comparison was made between the mean difference of pre- and post-treatment values of groups I and II, superior results were detected with the latter. The mean difference of WBCs in EPF among group II was 19 +/- 9.32 compared with 9.2 +/- 8.2 among group I. Post-prostatic massage urinalysis mean difference in group II was 7.2 +/- 1.99, whereas in group I it was 3.1 +/- 3.93. The uroflowmetric studies showed mean difference Q max to be 4.3 +/- 2.63 in group II, whereas in group I it was 2.0 +/- 1.33. From the above data, it was concluded that transrectal microwave hyperthermia improved the outcome of therapy of chronic abacterial prostatitis and provided a potentially effective therapeutic modality for this condition