Amniotic fluid interleukin - 6 [il-6] determination: a possible guide for management and prognosis of preterm labour
Medical Journal of Cairo University [The]. 1997; 65 (Supp. 4): 1-6
em Inglês
| IMEMR
| ID: emr-45876
ABSTRACT
Amniotic fluid samples were collected from four carefully selected groups of pregnant women, respectively, presented as followed [but none with any evidence of intrauterine infection] Group I, term pregnancy not in labor; group II, normal term labor; group III, preterm labor and undelivered within one week of sampling and group IV, preterm labor and delivered within one week of sampling. Amniotic fluid was obtained by amniocentesis [in undelivered women] or at the time of amniotomy [in delivered women]. The samples were cultured to detect any intrauterine infection. Interleukin-6 [IL-6] was determined by a specific enzyme-linked immunoassay. The mean [ +/- SD] amniotic fluid IL-6 levels [pg/ml] were 25.5 +/- 6.2 in group I, 504 +/- 60.6 in group II, 45 +/- 15.1 in group III and 406 +/- 100.7 in group IV. However, insignificant difference in the IL-6 levels was found between the women of group II and group IV, a significant difference was noticed in the IL-6 levels between the undelivered [groups I and III] and delivered [groups II and IV] women whether in term or preterm labor. Therefore, it was concluded that the determination of IL-6 level in amniotic fluid may help in the prognosis and management of preterm labor
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Complicações na Gravidez
/
Prognóstico
/
Amniocentese
/
Líquido Amniótico
/
Trabalho de Parto Prematuro
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Med. J. Cairo Univ.
Ano de publicação:
1997
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