Microbial transformation of emetine into o-methyl psychotrine
SPJ-Saudi Pharmaceutical Journal. 1997; 5 (1): 52-55
em Inglês
| IMEMR
| ID: emr-47049
ABSTRACT
Several microorganisms [fungi and bacteria] were screened for their ability to biotransform emetine. Cunninghamella blackesleeana MR.-198 was selected for scale-up transformation, as it showed a major transformation product and a small amount of unidentified minor product, in addition to untransformed emetine. The major metabolite was characterized using one and two dimensional NMR techniques as O-methylpsychotrine. Further confirmation was carried out by direct comparison with a reference sample prepared by methylation of psychotrine
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Técnicas Microbiológicas
/
Emetina
Idioma:
Inglês
Revista:
Saudi Pharm. J.
Ano de publicação:
1997
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