Influence of neostigmine and atropine on postoperative nausea and vomiting in day case surgery

ABSTRACT

Sixty healthy patients undergoing elective short surgery under general anaesthesia were randomly allocated into two groups Group A receive a mixture of neostigmine 1.5 mg and atropine 1 mg to anatagonize the residual muscle relaxant. Group B spontaneous recovery was allowed. The incidence of past-operative vomiting was assessed. There were no significant difference in frequency of nausea and vomiting between the two groups. The incidence of postoperative nausea was 22 in group A and 28 in group B, while vomiting was 14 in group A and 18 in group B.These results ensuring a decreased incidence of postoperative nausea and vomiting after antagonizing residual neuromuscular block by neostigmine and atropine, enable smooth recovery and early discharge from the hospital especially in day-case surgery