Synthesis and antitumor properties of some 9-benzylpurine derivatives
Egyptian Journal of Chemistry. 1998; 41 (1-6): 247-56
em Inglês
| IMEMR
| ID: emr-47912
ABSTRACT
During the past few years numerous synthetic purines have been claimed to have multitude of useful biological and pharmacological activities. For example, the antitumour [1-3] and antiviral [4,5]properties of many purine derivatives have been reported. Also, some alkoxy/aryloxycaffiene derivatives have been reported to exhibit cytostatic action against tumour cells in tissue culture [6]. Moreover, 6-methoxypurine has been proved to show activity at 250 and 125 mg/kg versus L 1210 leukaemia [7] Therefore, the interest in the present work was directed for synthesizing some newer purine derivatives with the target to evaluate their potential antitumour properties
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Compostos de Benzil
/
Antineoplásicos
Idioma:
Inglês
Revista:
Egypt. J. Chem.
Ano de publicação:
1998
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