Les Aplasies me'dullaires en me'decine interne [a'propos de 32 cas]

ABSTRACT

Our study was about 32 cases of medullary aplasia managed at the Ibn Sina CHU between 1990 and 1994. It's an uncommon disease but a dangerous one affecting mainly the young adult. It's manifested clinically at the variable degrees by an anemic, hemorrhagic and infectious syndrome. The diagnosis is indicated by hematologic disorders, but well confirmed by the bonymedullary biopsy. Although the origin for the major cases is unknown, the etiologic research has to be conducted because it helps partly for the prognosis. In all cases, an hematologic reanimation is necessary, whereas the androgenotherapy is the more effective option for low risk forms. In all the other cases, the bone marrow graft is the best treatment. The antilymphocytic serum can be the second alternative