Local anesthetic and antiarrhythmic activity of certain new 1,3,4-thiadiazole derivatives
SPJ-Saudi Pharmaceutical Journal. 1998; 6 (3-4): 228-34
em Inglês
| IMEMR
| ID: emr-49821
ABSTRACT
A series of 2-[1-oxo-2-[substitutedamino] ethylamino and 2- or 3-[substitutedamino] propylamino] 5 trifluoromethy1-1,3,4-thiadiazoles [5a-f, 6a-f and 7a-f] was synthesized and evaluated for their local anesthetic and antiarrhythmic activity. Some of the tested compounds showed promising activity. The detailed synthesis, spectroscopic and biological data are reported
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Tiadiazóis
/
Anestésicos Locais
/
Antiarrítmicos
Idioma:
Inglês
Revista:
Saudi Pharm. J.
Ano de publicação:
1998
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