Comparative study between intranasal midazolam and ketamine as a preanesthetic medication for children

ABSTRACT

The perfect pre anesthetic medication and its ideal route of administration are still debated, However for pediatric day-case surgery premedication is frequently omitted because of the fear that it will prolong the child's recovery and hospital discharge time. The effects or intranasal midazolam 0.2 mg.kg-1 and placebo were compared as regard to separation score, induction score, recovery time and hospital discharge time. Sixty children, ASA I and II, aged between 2 and 6 year undergoing a day case surgery, were randomly allocated into 3 groups separation and induction scores were satisfactory in midazolam [85%, 75%] and ketamine [80%, 70%] groups and poor in placebo [10% - 15%] [P < 0.05]. Recovery time was the same as the placebo. Also the hospital discharge time was nearly the same