Preoperative cervical cytology in endometrial carcinoma

ABSTRACT

We studied the correlation between preoperative cervical cytology, postoperative clinicopathologic findings, and sites of metastasis from 50 surgically staged patients with endometrial carcinoma Thirty-four patients [68%], had normal cervical cytology, and 16 [32%] had malignant preoperative cervical cytology. Malignant cervical smears were statistically correlated with surgical stage [P = 0.001], histopathology [P =0.010], tumor grade [P = 0.012]. depth of myometrial tumor invasion [P = 0.001], cervical involvement [P = 0.01], lymph node metastases [P = 0.002], and andexal metastases [P = 0.012]. Our study indicates that positive preoperative cervical cytology itself does not appear to be an independent prognostic factor and probably should not influence treatment decisions in endometrial cancer