Dysfunctional uterine bleeding: a clinicohistopathological analysis based

ABSTRACT

This study was conducted to identify the histopathological changes in patients of dysfunctional uterine bleeding [DUB], their response to different modes of treatment and their effects on maternal well being. Sixty eight cases diagnosed as DUB during a period of one year at Gynae unit II, Abbassi Shaheed Hospital, Karachi were included in the study. DUB was diagnosed in 10.46 percent of women admitted with gynaecological problems. Majority of women were multiparous and belonged to age group between 21 to 40 years. Commonest presenting symptoms were menorrhagia [32.35 percent] and polymenorrhagia [27.94 percent]. Commonest histopathological feature was secretory phase [52.46 percent] and then the proliferative phase. A good response to curettage only was achieved in 14.17 percent of patients, while majority [67.65 percent] needed medical treatment as well. Hysterectomy was performed in 36.76 percent of patients. The negative effect on maternal health was observed as anaemia in 88.23 percent women. Early diagnosis and treatment of DUB can reduce excessive blood loss and its impact on maternal health