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Familial cancers
KMJ-Kuwait Medical Journal. 1999; 31 (3): 240-245
em Inglês | IMEMR | ID: emr-51501
ABSTRACT
Although cancer is common in the general population, only a small proportion is thought to be due to highly penetrant cancer genes. Families with a highly penetrant cancer predisposing gene may be recognised by the presence of a high number of individuals within the family with a particular cancer type, or individuals with features associated with rare inherited cancers, such as retinal changes or multiple colonic polyps. It is likely that there are many other less penetrant genes, which, in combination with environmental influences, will confer a greater lifetime predisposition to cancers. These genes are currently being identified through epidemiological studies
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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Neoplasias Ovarianas / Retinoblastoma / Neoplasias da Mama / Neoplasia Endócrina Múltipla / Família / Neoplasias Colorretais Hereditárias sem Polipose / Síndrome de Li-Fraumeni / Polipose Adenomatosa do Colo / Doença de von Hippel-Lindau Limite: Humanos Idioma: Inglês Revista: Kuwait Med. J. Ano de publicação: 1999

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Índice: IMEMR (Mediterrâneo Oriental) Assunto principal: Neoplasias Ovarianas / Retinoblastoma / Neoplasias da Mama / Neoplasia Endócrina Múltipla / Família / Neoplasias Colorretais Hereditárias sem Polipose / Síndrome de Li-Fraumeni / Polipose Adenomatosa do Colo / Doença de von Hippel-Lindau Limite: Humanos Idioma: Inglês Revista: Kuwait Med. J. Ano de publicação: 1999