Inherited factor Vll deficiency [about one case]

ABSTRACT

Factor VII or proconvertine is a vitamin K dependent clotting factor which intervenes in the exgonic road of blood coagulation. Factor VII defect is an inherited disease with autosomic recessive transmission. It's a rare pathology, the incidence is estimated at 1/500000 of the general population. We report here a case of a 55 year old woman hospitalized for an anemia which occurred after dental extraction followed by hemorrhage. The paraclinical investigations found an isolated enlargement of Quick's time with a normal active cephalin time. The different clotting factors rates were measured and a striking factor VII defect was noted. By this observation, we wish to emphasize the clinical, biological and therapeutical particularities of this exceptional affection