Interleukin - 8 in chronic renal failure and patients on peritoneal dialysis

ABSTRACT

The present study included 35 subjects classified into four groups. Group 1 included 20 chronic uremic patients with ages ranged from 19 to 61 years, group 2 included 9 patients with chronic peritoneal dialysis with ages ranged from 35 to 61 years] and group 3 included 6 patients on chronic peritoneal dialysis without peritonitis aged between 45 and 57 years. They were compared with group 4 including 10 age and gender matched individuals with ages between 25 and 60 years. Complete history, clinical examination, complete urine analysis, serum urea, creatinine and creatinine clearance assessment and measurement of interleukin-8 assessment were done. It could be concluded that patients with renal failure had an increased serum IL-8 level. IL-8 concentration was higher in cases with peritonitis than those without. These results could be important in the subsequent disturbed immune status of these patients