Effect of monosodium glutamate on the nerve cells of adult male albino rat. histological study

ABSTRACT

Monosodium glutamate [MSG] is one of the food additives which modify the flavor of food. This study was done to detect the possible effects of monosodium glutamate in its recommended and high doses on both types of nerve cells motor and sensory. 30 adult male albino rats were used in this study. They were classified into the following groups Group I control group. Group II included animals which received the recommended dose of MSG 4 mg/gm of body weight/day orally for one month. Half of these animals were sacrificed after one month from MSG administration, while the rest of the animals were sacrificed 2 months after stoppage of MSG administration. Group III, in which the animals were given double dose of MSG 8 mg/gm of body weight/day orally for one month, 5 animals were sacrificed after one month from MSG administration. The other animals were sacrificed 2 months after stoppage of MSG administration