multivariate analysis of prognostic factors in patients with acute lymphoblastic leukemia

ABSTRACT

In this study, 31 patients with newly diagnosed acute lymphoblastic leukemia [ALL] were included. Their clinical and laboratory data were analyzed in order to determine the possible correlation between clinical presentation, morphologic subclasses, cytochemical reactions, immunological phenotypes and cytogenetic findings. The correlation between each of the previous parameters and the response to therapy was also examined. It was concluded that the extension of the classification of acute lymphoblastic leukemia to include clinical, morphological, immunophenotypic and cytogenetic analysis assisted in better prognostic outlook