Les manifestations cliniques et biologiques des leucemies aigues lymphoblastiques de l'enfant [etude retrospective de 87 cas]

We present in this study the clinical and biological datas of 87 children suffering from acute lymphoblastic leukemia followed between 1985 and 1996. The mean age was 7 years; 37% of the patients were aged under 5 years at diagnosis. The sex ratio was 1.35. the anemic, infection and hemorrhagic syndromes were observed in respectively 65%, 18% and 11% of the patients. Adenopathies were found in 70% splenomegaly and/ or hepatomegaly in 75% Hyperleucocytosis was found in 64%, anemia in 90% and thrombopenia in 85% of the cases. Using the FAB classification we found 72% type 1, 22% type 2 and 6% type 3 acute lymphoblastic leukemia. Cerebro- spinal fluid study revealed meningeal leukemic involvement in 17% of cases