Assessment of the role of soluble intracellular adhesion molecule-1 [sICAM-1] in the pathogenesis and as a marker of disease severity in different stages of human schistosomiasis and toxoplasmosis
Journal of the Egyptian Society of Parasitology. 2000; 30 (2): 537-545
em Inglês
| IMEMR
| ID: emr-54176
ABSTRACT
The role of soluble intracellular adhesion molecule 1 [sICAM-1] in the pathogenesis and its relevance to disease severity was assessed in different stages of human infection with S. mansoni, S. hematobium and T. Gondii. The levels of sICAM-1 obtained in the current study, correlated with disease severity degree of cell destruction and type of immune response. Highest sICAM-1 levels were observed in only two groups [hepatosplenic schistosomiasis and patients with mixed active S. Hematobium and T. gondii infections], while the other two groups [separate cases of active S. hematobium infection or latent T. Gondii infection] showed no significant rise in sICAM-1 levels
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Esquistossomose
/
Índice de Gravidade de Doença
/
Biomarcadores
/
Moléculas de Adesão Celular
/
Integrinas
/
Toxoplasmose
Limite:
Humanos
Idioma:
Inglês
Revista:
J. Egypt. Soc. Parasitol.
Ano de publicação:
2000
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