Valproate associated acute pancreatitis
Neurosciences. 2000; 5 (3): 156-158
em Inglês
| IMEMR
| ID: emr-54805
ABSTRACT
There is a definitive association between valproate therapy and acute pancreatitis. More than 50 cases have been reported. Most of the reported cases were mild yet there were a few more cases with higher morbidity and mortality. The risk is higher in patients under 20 years of age, during the first year of therapy, on the patient having encephalopathy or chronic renal failure and on patients with anti-epileptic drug polytherapy. The treatment of pancreatitis is supportive, laparotomy should be avoided. Re-challenge is hazardous and should be avoided
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Índice:
IMEMR (Mediterrâneo Oriental)
Assunto principal:
Pancreatite
/
Doença Aguda
/
Ácido Valproico
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Epilepsia
/
Anticonvulsivantes
Limite:
Humanos
Idioma:
Inglês
Revista:
Neurosciences
Ano de publicação:
2000
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