Applications of a new technique to achieve and maintain a rapid and constant plasma cimetidine concentration I

ABSTRACT

A new system has been employed in this experiment to achieve and maintain a rapid and constant plasma drug concentration. There is an excellent agreement between the in-vitro results fig. 3 and the in-vivo results table 3; these results obtained using the exponential infusion system provides a good approach that can be used in experimental work and can be applied clinically in the intensive care unit