Thyroid autoantibodies in euthyroid women with a history of recurrent miscarriage

ABSTRACT

To determine the prevalence of thyroid autoantibodies in women with a history of recurrent miscarriage, this study was carried out on twenty euihyroid women with a history of recurrent abortion and attending the Obstetrics and Gynecology Department of Tanta University Hospital. All serum samples were evaluated for the presence of thyroid peroxidase and thyroglobulin antibodies with the use of a standard, highly sensitive ELISA. Results of this study showed that 35% of women in the study group and 20% of women in the control group had positive assay results for either one or both of the thyroid autoantibodies. This means that thyroid autoantibodies were detected more frequently in women with recurrent miscarriage than in normal fertile women, and thus these antibodies can help in the detection of at risk pregnancy