increased levels of angiotensin and prostaglandin F2 in toxaemia of pregnancy

ABSTRACT

The present study dealt with 2 groups of pregnant women. First group comprised women suffering from Toxeamia of pregnancy and the other group of normal pregnant women. The age ranged between 25-27 years old. Peripheral blood samples were withdrawn at different phases of pregnancy and after delivery and was subjected to estimation of angiotensin, prostaglandin F2alpha and cholesterol level. Serum angiotensin level was higher in preeclamptic women than that in normal pregnant women during pregnancy while it tended to decline after delivery in preeclamptic women. Prostaglandin F2alpha showed elevated values, but it declined in preeclamptic cord blood. No changes were noticed for cholesterol levels in both groups of pregnant women. From the results it seemed that the increased levels of PGF2alpha and angiotensin may account for preeclamptic hypertension since 24 hrs after delivery, normal blood pressure were reassumed