Early and late haemodynamic effects of successful coronary angioplasty with coronary stenting on the mitral and aortic flow filling patterns assessed by pulsed doppler-echocardiography

ABSTRACT

Forty patients [31 males, 9 females], mean age [49.33 +/- 8.166 years] were selected for this study. Their clinical presentations were different 5 cases with highly positive stress test, 21 cases non-infarct and 14 cases infarct with clinical manifestations of instability. For all selected patients in this study, the coronary arteries lesions fulfilled the criteria for intervention with different anatomical site lesions. Successful angioplasty with coronary stenting was defined as 50% increase in luminal diameter with residual narrowing <40%. Doppler echocardiographic measurements were obtained before, within 24 hours, after three months of the procedure. Twenty healthy persons were taken as controls [15 males and 5 females with mean age 51.1 +/- 8.172 years]. Early effects of successful PTCA with coronary stenting on the mitral and aortic flow filling patterns were the diminution of isovolumic relaxation time [IVRT]. Peak aortic flow significantly increased and other variables insignificantly changed. However, after three months, the value of EF slope increased. Also, E/A integral ratio increased, and while A% integral decreased, E/A ratio increased. Acceleration and deceleration times significantly increased and aortic flow integral increased. The mean value of EF%, FS%, MVCF, SV, SVI, COPI insignificantly changed either early or late after revascularization