study of the possible hazards of acute and chronic exposure to microwaves on hepatorenal function and some blood trace elements in albino rats

ABSTRACT

Microwave exposure possess some degree of health hazards, the objective of the present study was the investigation of the possible effects of acute and chronic exposure to radiation on some liver, kidney, tissue antioxidants enzymes as superoxide dismutase, glutathione peroxidases, glutathione and toxic free radical lipid peroxide that results from stress oxidative tissues damage as well as the effect of microwaves on some trace elements that acts as metalloenzyme as zinc, selenium, copper and manganese. The result of the present study showed that exposure to microwaves [acute and chronic] produced significant reduction of antioxidant enzymes as superoxide dismutase, glutathione peroxidase and glutathione content. It also produced significant increase in toxic free radical malondialdehyde. These changes are more manifested with acute exposure [7 days]. The parameters of this study were improved with concomitant administration of DDB [well known antioxidant and tissue protective]. Also, the results showed that there was significant impairment of liver and kidney parameters with acute exposure and still there were changes in chronic which were insignificant. The parameters of liver and kidney were improved by the administration of DDB concomitantly