Asokarishta-Studies on Metabolism and Gastro-intestinal Motility

ABSTRACT

The 24 hours acute metabolic study revealed certain striking aspect of the pharmacological profile of Ascokarishta and Saraca asoca [Roxb]. Asokarishta causes no change in food intake but decreases the defecation rate and with low water intake maintains normal rate of excretion. But Saraca asoca [Roxb] causes no change in food intake and defecation followed by slight decrease in water intake but no difference on urinary output. The gastro-intestinal motility test revealed that Asokarishta did not change the motility at all, but Saraca asoca [Roxb] slightly increased the motility whereas the rest of the components lowered the motility. In 30 days chronic administration study all of the components slightly decreased the rate of gain in body weight compared to control