Prevalence of HLA- [B5andB27] in the Jordanian poplulation

ABSTRACT

screening for HLA- [B5andB27] is routinely carried out for kidney and bone marrow donors. The purpose of this study is to determine the prevalence of HLA- [B5andB27] among the Jordanian population compared with other population. patients and methods the present study was conducted on seven hundred and fifty four healthy kidney and bone marrow donors visiting the King Hussein Medical Center [K.H.M.C.], in the period from January 1994 to December 1998. This group was typed for both HLA- [B5andB27] antigens by serological method. the frequencies of HLA- [B5and B27] were 27% and 3.4% respectively. the frequency of HLA- [B5and B27] was higher in the Jordanian population compared with other population, such as the Caucasian who showed a prevalence of 6% and the African blacks who had a prevalence of 3% and close to the Japanese population, where a prevalence of 0.9% was reported. The frequency of [HLA-B27] on the other hand was low in the Jordanian population, compared to the Caucasian 6-10% and higher than the Japanese population where a prevalence of 0.3% was reported