Effect of acute exercise on serum malondialdehyde levels in physically trained and untrained apparently healthy people

ABSTRACT

1. To study and compare the changes in serum malondialehyde levels after an acute about of exercise between physically trained and untrained healthy people. Department of Physiology, Basic Medical Sciences Institute [BMSI], Jinnah Postgraduate Medical Center [LPMC], Karachi from June 1999 to May 2000. A total of 60 apparently healthy [30 males and 30 females] randomly selected subjects with a known history of regular physical exercise [i.e. trained control groups A and B respectively] and other total of 60 apparently healthy [30 males and 30 females] randomly selected subjects without history of any regular physical exercise [i.e. untrained Test groups C and D respectively] with age ranging between 18 to 40 years, underwent an acute bout of similar moderate intensity exercise of 30 minutes duration on a bicycle ergometer [after their age and body mass index matching]. Their pre and post exercise malondialdehyde levels were estimated and compared for statistical analysis. Serum malondialdehyde levels were significantly [P< 0.05] increased in both control and test subjects at the of an acute of physical exercise as compared to their basal levels. There was a significant [P< 0.05] decrease in 1-hour post exercise serum malondialdehyde levels in control group [A and B] subjects as compared to their immediate post exercise levels. However, no such decrease was found in test group [C and D] subjects whose 1-hour post exercise serum malondialdehyde levels remained almost the same as compared with their immediate pot exercise levels. Exercise-training results in decreased 1-hour post-exercise serum malondialdehyde levels as compared to their immediate post exercise levels in physically trained healthy people in comparison to untrained apparently healthy people