Study of some antioxidants in cases of bronchial asthma

ABSTRACT

The aim of this study was to explore some of the local antioxidant defenses in patients with asthma focusing on superoxide dismutase [SOD], glutathione [GSH] and selenium. Two groups of subjects were included in this study Group I included 20 asthmatic patients and group II included 10 normal control subjects. Glutathione [GSH], superoxide dismutase [SOD] and selenium were estimated in bronchoalveolar lavage [BAL] of all subjects. The results showed that there was a significant increase in the level of BAL glutathione among asthmatic group as compared with the control group. Also, the study showed a significant decrease in the level of BAL selenium among the asthmatic group as compared with the control group. Also, there was a significant decrease in the level of BAL superoxide dismutase among the asthmatic group when compared with the control group