Tepid blood cardioplegia versus cold crystaloid cardioplegia for myocaridal protection

ABSTRACT

The tepid blood cardioplegia 29°C was recently introduced. It reduce anaerobic myocardial lactate and acid release without inhibiting rnyocardial activity. The aim of this study is to compare tepid blood cardioplegia versus cold crystalloid cardioplegia for rnyocardial protection. 40 patients undergoing double valve replacement, 20 patients receive intermittent antegrade cold crystalloid and 20 patients receive tepid cardioplegia. Data collection included Aortic cross clamp time, bypass time, spontaneous recovery or the use of defibrillator, number of DC shock used and need for inotropic support. Measuring cardiac enzymes [CK-MB], the myoglobin and cardiac troponin was done. There was significant difference between two groups as regard to the behaviour of myocardial activity at end of cardiopulmonary bypass in all parameters [P <0.001]. So we conclude that tepid blood cardioplegia is safe, efficacious method of rnyocardial protection when compared with cold crystallod cardioplegia